Author Topic: Comparison of our HRT Blood Test Results  (Read 12740 times)

0 Members and 2 Guests are viewing this topic.

Offline JanePlain

  • M2E2?2->ME
  • *
  • *
  • Posts: 648
  • Reputation: +9/-0
  • Gender: Male
  • Finished questioning...
Re: Comparison of our HRT Blood Test Results
« Reply #280 on: February 23, 2020, 02:59:37 pm »
Hi

I have my 6month test results on oestrogel (12 month on any oestrogen). These were taken at 8 hours after application, so are very low but done to determine if I required more to keep my levels constant. so (UK units)
Oestradiol 84
Testosterone 2.8

On the back of these results the endocrine has now doubled my dose. YAY! and I apply it twice a day to maintain the level.
Still having really good results on the gel too. Next results will not be until September now, I am on 6 month checks from here.

Oh, they also switched me from testogel to tostran, as it is a much lower dose and avoids the peaks I was having with testogel (I need to take some T, despite being MtF due to producing none at all). This also seems a much better solution and more in line with cis-female post-menopause HRT in the UK.


Is it out of line to ponder keeping the estrogen and testosterone levels normal for pre menopausal women? 

Ugh... 0 testosterone was just like injecting depression, mood issues and total lack of energy for me.

Offline Pammie

  • *
  • Posts: 1,996
  • Reputation: +14/-0
Re: Comparison of our HRT Blood Test Results
« Reply #281 on: February 23, 2020, 03:10:46 pm »

Is it out of line to ponder keeping the estrogen and testosterone levels normal for pre menopausal women? 

Ugh... 0 testosterone was just like injecting depression, mood issues and total lack of energy for me.
My T is pretty much 0 and I’ve never felt better physically or mood wise  - of course YMMV


I opened the door and the light shone in

Offline SarahEL

  • Oh no, I have said too much, I haven't said enough...
  • Friend
  • ****
  • *
  • *
  • Posts: 353
  • Reputation: +10/-0
  • Gender: Female
  • That's me in the corner.... That's me in the photo
Re: Comparison of our HRT Blood Test Results
« Reply #282 on: February 24, 2020, 06:15:21 pm »
My endocrine issues are not normal in the slightest. Having pretty close to 0 T is not the same as having none at all. Most people produce T from other areas of their bodies, adrenals being one such place. What is usually measured is Free T, or the T available in the blood - this does not quite give you the full picture, but is enough for anyone with a functioning endocrine system. I produce no LH, FSH or SBGH hormones naturally (amongst others) so for me there is an actual need to have T in my system and put it there artificially.

That said, I do wonder why some endo's like the T to be as low as possible when transitioning? Most cis-females have a significant level of T in their systems and it doesn't masculate them to any extent. Obviously not as high as cis-males but still a lot higher than a lot of MTF targets I have seen posted on here? A female with low T has a low sex-drive and gains little satisfaction, Is usually depressed, lethargic and feels very weak.

When I apply my T-gel I get a real sense of dread and hate - it seems to me to be counter-intuitive and I feel a repulsion for doing so - But biochemically it is vitally important I do so (and as I said, I am unique in this) but also there are benefits to being female and having correct T levels...
Oh, life is bigger,  It's bigger Than you and you are not me
The lengths that I will go to.  The distance in your eyes

R.E.M. - Losing My Religion

Offline Maddie

  • Family
  • *
  • Posts: 1,894
  • Reputation: +14/-0
Re: Comparison of our HRT Blood Test Results
« Reply #283 on: February 27, 2020, 09:24:03 am »
SarahEL your posts make me think hard about counterintuiition with hormones and what's going on with me.
My T is low without any blocker, yet I show just tiny development on E in 7 months.  Believe my T has always been very low, yet I looked very masculine, lots of facial hair etc

Offline Tamara Tilly

  • Friend
  • ****
  • Posts: 183
  • Reputation: +2/-0
Re: Comparison of our HRT Blood Test Results
« Reply #284 on: March 03, 2020, 02:35:05 am »
Pamela can you just remind me what you mean by International and US? Any chance of just popping the proper scientific measurements on here again so that I can cross-reference? What is pmol/L for estradiol by your way of referencing and what is nmol/L for testosterone in your system?

Not meaning to take a pop, but just find 'international' and 'US' very confusing as no-one in laboratories or WHO uses them.

xx

Offline pamelatransuk

  • Finally taking action after decades of suppression
  • *
  • Posts: 2,279
  • Reputation: +11/-0
  • Gender: Female
Re: Comparison of our HRT Blood Test Results
« Reply #285 on: March 03, 2020, 04:16:25 am »
Hi Pamela, thanks.

By Intl you mean pmol/L?
And by US you mean ? pg/ml?
Pamela can you just remind me what you mean by International and US? Any chance of just popping the proper scientific measurements on here again so that I can cross-reference? What is pmol/L for estradiol by your way of referencing and what is nmol/L for testosterone in your system?

Not meaning to take a pop, but just find 'international' and 'US' very confusing as no-one in laboratories or WHO uses them.

xx

Hello again Tamara

I confirm pmol/L and nmol/L are the Intl measurements for E and T respectively. We always use them in UK and hence yours should be measured so.

I confirm pg/ml and ng/dl are the US measurements for E&T respectively.

Conversion tool at reply 121. Hope this helps.

Hugs

Pamela  xx







Offline Tamara Tilly

  • Friend
  • ****
  • Posts: 183
  • Reputation: +2/-0
Re: Comparison of our HRT Blood Test Results
« Reply #286 on: March 03, 2020, 04:46:39 am »
Yes although I can't see why there's imposition of non-scientific terminology when the science of endocrinology is so important in transitioning. It's even more important when you consider that there are other units of measurement in blood tests. I'd much rather stick to laboratory measurements even when there are multiple units of measurement. For those who don't live in the UK or US it gets even more confusing.

Hey ho. Each to their own I guess.


Offline pamelatransuk

  • Finally taking action after decades of suppression
  • *
  • Posts: 2,279
  • Reputation: +11/-0
  • Gender: Female
Re: Comparison of our HRT Blood Test Results
« Reply #287 on: March 03, 2020, 07:08:06 am »
As far as I am aware, most countries outside US use Intl measurements of E&T as above - Canada, Australia, New Zealand, Europe and therefore we should only have 2  (instead of more) to confuse us!

However more confusing to me is that there is such a significant difference in the Target E&T BT Levels for Transwomen even within geographical locations within UK, within States of US, between different endos who have (quite understandably of course) different viewpoints.

Hugs

Pamela  xx






Offline Tamara Tilly

  • Friend
  • ****
  • Posts: 183
  • Reputation: +2/-0
Re: Comparison of our HRT Blood Test Results
« Reply #288 on: March 04, 2020, 01:29:54 am »
Agreed, Pamela. I've had situations too where reputable endocrinologists have said completely opposite things and on many occasions they, and other medics, have sought a steer from me. I know part of it is about listening to how a patient feels in themselves but the lack of consistent science is one of our problems I feel.

Hugs back xx

Offline Jenny_Oh

  • Friend
  • ****
  • Posts: 204
  • Reputation: +5/-0
  • Gender: Queer
Re: Comparison of our HRT Blood Test Results
« Reply #289 on: March 04, 2020, 11:37:27 pm »
However more confusing to me is that there is such a significant difference in the Target E&T BT Levels for Transwomen even within geographical locations within UK, within States of US, between different endos who have (quite understandably of course) different viewpoints.

I think part of the problem is that despite an emphasis on evidence based medicine, there is a dearth of evidence on which to base a program of HRT for transmen and women. Couple that with the patient's desire to see rapid results, the informed consent model on which many HRT programs operate for transgender individuals and the use of E2 and P4 to control T and you end up with exactly what you describe. A wide variety of blood hormone levels and recommendations from different doctors.

Sisterly hugs,
Jennifer

Offline Allie Jayne

  • *
  • Posts: 1,780
  • Reputation: +17/-0
  • Gender: Female
Re: Comparison of our HRT Blood Test Results
« Reply #290 on: March 04, 2020, 11:47:51 pm »
Pamela,
             I just got my 12 month blood levels from my GP.

Oestradiol 135 pmol/l

Testosterone. 0.4 nmol/l

I am back within the normal male range for Estradiol and to say I am disappointed with my Endo would be a huge understatement.

Hugs,

Allie

Offline pamelatransuk

  • Finally taking action after decades of suppression
  • *
  • Posts: 2,279
  • Reputation: +11/-0
  • Gender: Female
Re: Comparison of our HRT Blood Test Results
« Reply #291 on: March 05, 2020, 04:31:52 am »
Thank you Allie for your latest BT results which I have added to your table as below. I know this a trough reading as most of are requested to provide (but your present endo usually seeks mid-point reading).

I am truly sorry that your endo is failing you and that it may be necessary to find a new one.

Wishing you success both on your future BTs and on your transition as a whole with whomever you select as endo.

I know you are going fulltime shortly and of course that will uplift you greatly!


                        E (Intl)           E (US)           T (Intl)           T (US)

                         137                  37                 6                   173          After 2 months

                         117                  32                 0.5                  14          After 4 months

                         211                  58                0.3                    9           After 6 months

                         558                152                0.3                    9           After 8 months

                         135                  37                0.4                   12          After 12 months

Hugs

Pamela  xx
« Last Edit: March 05, 2020, 08:27:58 am by pamelatransuk »






Offline davina61

  • *
  • Posts: 4,994
  • Reputation: +12/-0
  • Gender: Female
  • The ramblings of an old dear
Re: Comparison of our HRT Blood Test Results
« Reply #292 on: March 06, 2020, 11:32:04 am »
have my latest bloods, E serum oestradiol 575 pmol/L and T .8 nmol/L  The T is up but this was taken same time as my 12 week anti T inj so that's expected to rise. Recon that was a mis print/ bad test on the E last time .
a long time coming (out) HRT 12 2017


Jill of all trades mistress of non
Know a bit about everything but not enough to be clever

Offline ChrissyRyan

  • “Have a gentle manner”
  • Family
  • *****
  • Posts: 26,957
  • Reputation: +33/-0
  • Gender: Female
  • No act of kindness, however small, is wasted.
Re: Comparison of our HRT Blood Test Results
« Reply #293 on: March 07, 2020, 12:17:56 pm »
Pamela,   @pamelatransuk

I am curious.  What I say may seem at least partially obvious or intuitive; but, I will go on.   :)

Perhaps our dosages, managed by knowledgeable physicians, are to change, first to help develop female body features, then to maintain them, and maybe (I hope) to avoid cancers, such as breast cancer.  Mammograms and breast exams can help us in regards to the potential or realized cancer, but cancer still is scary.

While we may all like the idea of having E to change our bodies, maybe as fast as practical, or hopeful!, perhaps dropping the E levels to the least possible later on would be good to avoid some of the cancer risk.

If someone can post or repost or link us to current related medical research literature concerning exogenous estrogen’s risk for cancer for MTFs, that might make for some good reading.  I think this information has been posted before here on various topics, but perhaps newer related research is also worth reading along with the best less current related research.

Hugs,   :)

Chrissy
Always be kinder than needed.  Be tender to others.  You are as beautiful as the thoughts you think and the words that your speak.   Always stay cheerful, be polite, kind, and understanding.  Knowledge and action shown without love is not impressive.  If you look for the good in people you will find it. Healthy relationships are so important to good living.

Good living, joy, unity, love, and happiness can come from following these practices: Never let selfishness or conceit motivate you.  Regard others as more important than yourself.  Do not limit attention to only your interests, but include the interests of others

It is not usually about how fast you transition, it is about how well you transition.  

Offline pamelatransuk

  • Finally taking action after decades of suppression
  • *
  • Posts: 2,279
  • Reputation: +11/-0
  • Gender: Female
Re: Comparison of our HRT Blood Test Results
« Reply #294 on: March 08, 2020, 05:39:59 am »
Pamela,   @pamelatransuk

I am curious.  What I say may seem at least partially obvious or intuitive; but, I will go on.   :)

Perhaps our dosages, managed by knowledgeable physicians, are to change, first to help develop female body features, then to maintain them, and maybe (I hope) to avoid cancers, such as breast cancer.  Mammograms and breast exams can help us in regards to the potential or realized cancer, but cancer still is scary.

While we may all like the idea of having E to change our bodies, maybe as fast as practical, or hopeful!, perhaps dropping the E levels to the least possible later on would be good to avoid some of the cancer risk.

Hugs,   :)

Chrissy

Hello again Chrissy

Your assumption seems reasonable to me; take it in three stages - develop features, maintain and enhance, possibly reduce to avoid potential cancer.

In terms of research literature, KayXo visits HRT Board periodically and provides previous and current research. You may wish to check her recent posts.

Hugs

Pamela  xx






Offline pamelatransuk

  • Finally taking action after decades of suppression
  • *
  • Posts: 2,279
  • Reputation: +11/-0
  • Gender: Female
Re: Comparison of our HRT Blood Test Results
« Reply #295 on: March 08, 2020, 05:46:43 am »
Thank you Davina for your BT results after 26 months which are:

E 575 (Intl) 157 (US) T 0.4 (Intl) 12 (US).

I am so glad you resolved the situation from a month ago and that your readings are good.

Hugs

Pamela  xx






Offline Tamara Tilly

  • Friend
  • ****
  • Posts: 183
  • Reputation: +2/-0
Re: Comparison of our HRT Blood Test Results
« Reply #296 on: March 09, 2020, 02:59:09 am »
I think part of the problem is that despite an emphasis on evidence based medicine, there is a dearth of evidence on which to base a program of HRT for transmen and women. Couple that with the patient's desire to see rapid results, the informed consent model on which many HRT programs operate for transgender individuals and the use of E2 and P4 to control T and you end up with exactly what you describe. A wide variety of blood hormone levels and recommendations from different doctors.

Sisterly hugs,
Jennifer

Such a good post x

Offline pamelatransuk

  • Finally taking action after decades of suppression
  • *
  • Posts: 2,279
  • Reputation: +11/-0
  • Gender: Female
Re: Comparison of our HRT Blood Test Results
« Reply #297 on: March 09, 2020, 04:55:52 am »
I think part of the problem is that despite an emphasis on evidence based medicine, there is a dearth of evidence on which to base a program of HRT for transmen and women. Couple that with the patient's desire to see rapid results, the informed consent model on which many HRT programs operate for transgender individuals and the use of E2 and P4 to control T and you end up with exactly what you describe. A wide variety of blood hormone levels and recommendations from different doctors.

Sisterly hugs,
Jennifer

Jennifer

I agree absolutely. You and Tamara and I are one on this.

Sisterly Hugs back

Pamela  xx






Offline Tamara Tilly

  • Friend
  • ****
  • Posts: 183
  • Reputation: +2/-0
Re: Comparison of our HRT Blood Test Results
« Reply #298 on: March 13, 2020, 02:27:29 pm »
Blimey. Latest blood results. Eeeek. 4 hours after application of T dose. Fasting test.

Pamela can you do your conversion thing on these? Thank you :) x

Three abnormal results are:

Oestradiol  3117 pmol/L

Sex Hormone-Binding Globulin 29.3 nmol/L

Testosterone 400 nmol/L

The rest normal:

TSH 1.85 mIU/L 1.85
Thyroxine T4 16.7 pmol/L
Prolactin 241 mU/L
Luteinising Hormone LH 6.66 IU/L
Follicle Stimulating Hormone (FSH) 10.2 IU/L
Cortisol 389 nmol/L

Can anyone tell me asap if they think these are cause for concern?  :o

I did these tests privately through a finger prick test, posted off. I'm wondering if this is suspect to be honest.

Offline Jenny_Oh

  • Friend
  • ****
  • Posts: 204
  • Reputation: +5/-0
  • Gender: Queer
Re: Comparison of our HRT Blood Test Results
« Reply #299 on: March 13, 2020, 10:27:36 pm »
Tamara,

Not trying to tread on Pamela's toes but,

E2 3117pmol/L (Int) is 849pg/mL (US)
T at 400nmol/L (Int) is 11536ng/dL (US)

Those number are insane, I would suspect the test result before worrying that anything is wrong.



Tags: Cycling HRT