Author Topic: Comparison of our HRT Blood Test Results  (Read 24882 times)

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Offline pamelatransuk

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Re: Comparison of our HRT Blood Test Results
« Reply #440 on: December 05, 2021, 12:49:56 pm »
Hello Ronniekylie and Welcome to this wonderful website. Always nice to meet another UK Member like myself - I live in Liverpool and started HRT in February 2018 and had GRS MDV last June.

Your E of 868 Intl converts to 236 US and your T of 0.5 Intl converts to 14 US.

Wishing you every happiness and success on your journey.

Hugs

Pamela xx

Offline ronniekylie90

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Re: Comparison of our HRT Blood Test Results
« Reply #441 on: December 05, 2021, 04:00:30 pm »
Hi Pam, thanks for the lovely message and for welcoming me. I've actually lived in Liverpool for 3 years in my late teens years. I am now 30 and been living down south (London)

thanks for converting, I have been medically transitioning ... well I started my 9th month a few days ago :) and I've never felt better actually.


Offline SoCal_Holly

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Re: Comparison of our HRT Blood Test Results
« Reply #442 on: December 10, 2021, 02:41:51 pm »
Happy Holidays!

My latest blood tests results 30 November.

Testosterone 70
Estrogen 126

Taken 6 hours after oral estradiol.

Offline pamelatransuk

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Re: Comparison of our HRT Blood Test Results
« Reply #443 on: December 10, 2021, 05:55:00 pm »
Thank you Holly for your BT results which I have tabulated below

                                                          E (US)              E (Intl)            T (US)            T (Intl)

Start                                                   14.5                  53                   553                 19.2

After 2.5 months                              49.5                 182                   80                    2.8

After 5.5 months                              80.5                 296                  305                 10.6

After 8.5 months                              70.4                 258                   90                    3.1

After 11 months                               60                    220                   282                  9.8 

After 14 months                               90                    330                  157                   5.4     

After 17 months                              126                  463                    70                    2.4   

Wishing you every happiness and success on your journey. Happy Holidays to you too.

Hugs

Pamela xx
             
           

Offline pamelatransuk

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Re: Comparison of our HRT Blood Test Results
« Reply #444 on: December 22, 2021, 04:43:48 pm »
Hello Everyone

Sorry for the delay but only today did I receive my BT results from December 2nd; I have never before known a 20 day wait for lab results. My E dosage was increased in September but my latest E result shows little difference. I shall wait for my next BT around March 2nd and take it from there.


                             E (Intl)          E (US)          T (Intl)          T (US)

After 3 Months           922              251                1.6               46

After 6 Months          1662             453                2.4               69

After 9 Months           442              120                0.7               20

After 12 Months         558              152                0.2                 6

After 16 Months         242                66                0.4               12

After 19 Months         819               223               0.2                 6

After 22 Months         941               256               0.3                 9

After 25 Months        1480              403               0.3                 9

After 28 Months        1403              382               0.5                14

After 31 Months         804                219              0.5                14

After 34 Months         656                179              0.5                14   

After 42 Months         463                126              0.3                  9        First Post Op

After 46 Months         481                131              0.4                12

Wishing all readers of this thread a Very Happy Christmas.

Hugs

Pamela  xx

Offline Chloe

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Re: Comparison of our HRT Blood Test Results
« Reply #445 on: December 23, 2021, 08:29:27 am »
      Oh dear, tested with Quest again on Dec 10th and E / SHBG results slowly coming DOWN but still way 'out of range'.. due many years of 'tabs'?
ESTRADIOL 714 H pg/mL
ESTRADIOL, FREE 7.65 H pg/mL
SEX HORMONE BINDING GLOBULIN 467 H nmol/L (Reference Range: 22-77)


      Took upon self, per NP's reluctance to ask many months ago, and COMPLETELY STOPPED all IM's as of Dec 4th, almost a month ago. Both 'T' still look 'ok'..
TESTOSTERONE, TOTAL, MS 31 L ng/dL (Reference Range: 250-1100)
DIHYDROTESTOSTERONE, LC/MS/MS 9 L ng/dL (Reference Range: 12-65
)

.. but plan to resume again post another requested test after New Years? Also requested a prescription for PROGESTERONE, will see what gives after email reply.

(ahh must wait 'til next year anyway! An 'auto email reply': "The office is closed from Wednesday December 22nd at 5 pm to January 4th at 9 am.  The lab will be open.. "

Merry Christmas!
« Last Edit: December 23, 2021, 01:20:50 pm by Chloe »
"But it's no use now," thought poor Alice, "to pretend be two people!
"Why, there's hardly enough of me left to make one respectable person!"
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Offline pamelatransuk

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Re: Comparison of our HRT Blood Test Results
« Reply #446 on: December 23, 2021, 12:31:24 pm »
Thank you Chloe.

Your E reading of 714 US converts to 2621 Intl and your T reading of 31 US converts 1.1 Intl.

Wishing you a Very Happy  Christmas.

Hugs

Pamela xx

Offline JanePlain

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Re: Comparison of our HRT Blood Test Results
« Reply #447 on: December 28, 2021, 03:46:21 pm »
Date             Estrogen in pg/ml
7/3/2017           ???   (Started HRT)
3/31/2018           51
10/1/2018           90
7/29/2019           158
11/29/2019       280
3/3/2020           312
7/2/2020           895
9/29/2020           443
10/28/2020       787
11/27/2020       391
12/29/2020       660
1/23/2021           559
6/1/2021           532

Okie dokie, I've finally decided to try and share my numbers with y'all.  I used patches for the first two years of my transition.  My labs dated 7/29/2019 was when I got an orchi and I began working with a new dr and we switched to implanted E pellets.  With patches I never had peeks and troughs, my E was super low, but always just a constant.  Now with pellets I have a cycle that can last anywhere from 3 - 6 months and possibly longer.  My first doctor felt that at 158 pg/ml was a perfect place for my E, my new dr felt I was estrogen starved and we began ramping things up according to how I felt and not just the numbers.  At 158 pg/ml I felt old, sluggish, tired, low libido.  At 895 pg/ml I felt like a rock star! Super high energy, high libido, felt like I did when I was in my early twenties and still operating on T.  Oh my T btw tends to be around 10-20 (sorry I forget the units.)

After now operating on E pellets for 2 years my Dr and I have set my goals to be roughly a trough level of 400 pg/ml and a peek level of 900 pg/ml, with about 5 months or so of levels maintained above 700 pg/ml.

Oh in 2020 we did a lot more labs as we were trying to more closely document how my body responds to the E pellets.

There ya go, do with it as you will.  :)

I like your new doctor!  He/She sounds like a good one.

Pamala's thread has so much data I thought I would look over some of it to puzzle out some technical questions in my head.  However your statement about taking some microscopic dose and the doctor saying "your fine" and not even exploring going higher made me sit back.  Why?  Why does this first doctor think that the results are meaningless that there is some lab number (Which looks like a cis woman in menopause) is the desired level?  I like whoever it is you saw after this dud who said to adjust until you felt good.  If only other doctors would do that for a wide variety of things!  If your in major pain does the doctor put you on some "dose" that does nothing?  Well I suppose some do actually but my point is just this.  What harm is having higher levels of estrogen going to do?  I've been told you can go overboard with testosterone in attempts to "bulk up" and look like Arnold and hurt yourself but estrogen really doesn't have that baggage.  So is it the financial cost?  Is insurance unwilling to pay for higher doses?  Is it just the mindset of using the minimal dose to achieve a number / who cares about the non effect (That doesn't really enhance someones life?)   

And maybe Pamala or one of the others can help me understand something.  I understand the different standards used in the US versus the UK but in either system finding the range that is considered lab "normal" seems to be a totally random thing.  US labs seem to have no two that agree.  And overseas labs seem to be no different.  Oh.... last question which I almost forgot.  Isin't the time you do the blood draw and how you are doing hormone replacement going to change the results by a large margin?  Say you take OEstrogel once a day at 9AM and have labs done at noon.  How different will it be if you do the same total amount of OEstrogel in split doses at 9am and 9PM and have the labs done at 10 AM?  Would the lab results even be close?  I don't know myself but I think it would be quite a bit different even if you took the same exact dose but had blood drawn at different times of the day or???  does it become more steady state?

For the doctors insisting you ladies be given menopausal levels of estrogen I think its wrong.  With men the gents with high end normal ranges are the gents golfing at age 85 versus fellows with low levels being pretty much vegged out.

I guess I could add the number of doctors that seem to think reducing your testosteone levels to as close to zero aren't doing you any favors.  It (Testosterone) might seem like the enemy but isn't the point to get yourself into healthy cis female normal levels???

"This world is but canvas to our imaginations.
Henry David Thoreau - (1817-1862)

Offline Nadine Spirit

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Re: Comparison of our HRT Blood Test Results
« Reply #448 on: December 29, 2021, 08:16:59 am »
Hi Jane -

My first dr did not specialize in transgender hormonal care, she is an OB/GYN and considers herself to be first and foremost a baby catcher as she described it.  She gave me the same amount of estrogen that she was giving to my cis female wife.  Eventually she had me up to twice my wife's dosage.

My current doctor specializes in transgender hormonal care.  She will also see cis clients, but most are male, female, and non binary transgender clients.  It makes a difference.  My estrogen is now way higher, and being as I lack a uterus, I can tolerate those higher levels without it affecting my menstruation as it does with my wife. 

I think the biggest problem is that we don't have enough medical transgender specialists.  My first doctor is the only one caring for trans women's HRT needs in all of the San Joaquin Valley (a huge portion of the interior of California.)  She is my closest resource for trans care, which is why I went to her first.  My current doctor is a four hour drive to Orange County.  And she does not take insurance.  It is an expense that many cannot handle.

Offline RandiL

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Re: Comparison of our HRT Blood Test Results
« Reply #449 on: December 29, 2021, 09:58:47 am »
@JanePlain and @Nadine Spirit, this is a very interesting discussion and relevant to many of us.

Jay asked about the risks of high E levels. I am also interested in this. Blood clots are what I've heard most about. But are those actually a risk for those who use injection or implanted pellets?

I use IM injections on a weekly basis. Jay, the most common practice is to draw blood at the trough for consistency, so I draw just before my weekly injection.

Nadine, I'm fascinated by your doctor going by how you feel, rather than any specific letter.

My HRT doc specializes in HRT but I think most of her clients are elderly cis women. She does however have many trans patients and is well respected in the local community.

My E levels have been in the 400's for the last 9 months which she thought was too high. So she cut my dose in half. We'll recheck in a month.

My smartphone thinks it's smarter than me. It's probably right.

Forging my new, best life as Randi

My personal blog thread: Randi the lost traveler, finding the right road at last

My HRT thread: Randi's HRT Journal


Offline JanePlain

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Just some grumbling about the medical "art"
« Reply #450 on: December 29, 2021, 07:15:03 pm »
Humm... I believe the panic over women taking estrogen after menopause was due to a very flawed study which only used Equine Hormones aka Female Horse Urine tablets which is horse estrogen not exactly bio identical to human estrogen.  And instead of doing their study on women who had recently gone into menopause they gave large doses to women of all ages so little old ladies that had been in menopause for decades were filled with youthfull levels of synthetic horse urine and some had heart attacks or strokes.  Personally I think this would have been the expected result not a surprise.  What does surprise me is never have they tried a study with one of the many actually identical to human estrogen treatments like *Everything other than Equine Hormone Tablets which if nothing else are very hard on your liver.  So I would say in all my total (not) an expert not to be too worried if your taking estrogen made for humans.  I would say that halving your dose if it halves you blood levels will put you in the upper end of normal range for men or women in menopause.  What I think you want is to be in the youthfull female range so you have a female puberty with the associated development.  But I'm not a doctor nor do I really know this stuff enough to do more then give my 2 cents worth and ask very obvious questions.  Oh! I'm told the answer to the Pills versus human identical hormones is that the horse estrogen pills can be patented.  Human estrogen was designed by "God" and he/she doesn't need lawyers and patents.  The thing being patented now is often how its applied.  Patch, Spray, Gel, Arm Pit goo and so on.  But the (I think) Bad result of this study is that doctors are far less likely to prescribe estrogen for women in menopause just as the genius study about PSA tests showing it could give false positives resulted in Doctors not doing PSA tests unless asked and thus... The only test there is wasn't used so.... Well its so obvious saying it but more men had advanced stages of cancer before it was diagnosed with the only other test which is reaching up your arse and feeling around for lumps. SIGH...

Everytime some study results in less treatment or less used of something it means lower costs to the insurance company so I tend to view all studies that conclude we should not do ___________ anymore highly questionable.  And if the people in the group studying the PSA test (for example) are all NOT urologists?  Really???  I wonder if the horse urine pills study had any endos?  I would not surprise me if it didn't.

"This world is but canvas to our imaginations.
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Offline Chloe

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Re: Comparison of our HRT Blood Test Results
« Reply #451 on: January 01, 2022, 06:36:39 am »
      *sigh* waiting for doc office to reopen on the 4th, two webmails later still impatiently waiting for 'reply'  :( Been rough cold-turkey off HRT for a month after so many years, *minor occasional headache*, *very weak/dizzy low energy* but otherwise surviving 'ok' ..

      Hair seems more oily & been tad bitchy, asserting self more? So-called "accepting ex-spouse" is fast becoming a huge problem plan on talking to a lawyer soon 'bout moving her OUT>:(
"But it's no use now," thought poor Alice, "to pretend be two people!
"Why, there's hardly enough of me left to make one respectable person!"
( Current read: Manly Gay VS Cute Pretty T )

Offline Chloe

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Re: Comparison of our HRT Blood Test Results
« Reply #452 on: January 14, 2022, 01:20:24 pm »
     *sigh* Had televisit today & no changes, no 'P' either right now must wait another 3 months! While E level has come down dramatically to 87pg/mL since taking last month OFF, NP now wants to get my SBHG level down which we did not test at all this last time around . .

Draw prior, in early Dec, SBGH was down a tad @ 467nmol/L but still way too high.

Quote from: wikipedia SBHG
     Testosterone and estradiol circulate in the bloodstream, loosely bound mostly to serum albumin (~54%), and to a lesser extent bound tightly to SHBG (~44%). Only a very small fraction of about 1 to 2% is unbound, or "free," and thus biologically active and able to enter a cell and activate its receptor. SHBG inhibits the function of these hormones. Thus, bioavailability of sex hormones is influenced by the level of SHBG

Oh Well! Bottom line -> the lower one's SBHG level the more effective 'E therapy' works! (ps edit: They want to put me on 'pellets', an in-person visit for sure, told her let's wait and see when better 'stabilized'.)
"But it's no use now," thought poor Alice, "to pretend be two people!
"Why, there's hardly enough of me left to make one respectable person!"
( Current read: Manly Gay VS Cute Pretty T )

Offline Ginger Tea

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Re: Comparison of our HRT Blood Test Results
« Reply #453 on: January 14, 2022, 03:12:25 pm »
Hi Pamela,

I thought I would send you my numbers. It’s very interesting how varied
the numbers are for everyone. My E shot up and I’m not sure why, I don’t
really feel any different. Anyway my doc wants to test again in a month,
so we’ll see.

Month 0
July 26,21 first day HRT
E-28
T-342
3 month 10/26/21
E-36
T-379
5 month plus a week
Just received result yesterday
E-853
T-248

So as you can see E went nuts,😂
I will send in next months numbers.

Thank You so much,
Sheila

Offline pamelatransuk

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Re: Comparison of our HRT Blood Test Results
« Reply #454 on: January 14, 2022, 03:20:52 pm »
Chloe

Noted with many thanks.

Quite a drop in E from 714 (US) 2621 (Intl) to 87 (US) 319 (Intl)!

Good luck for April Blood Tests.

Hugs

Pamela xx


Offline pamelatransuk

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Re: Comparison of our HRT Blood Test Results
« Reply #455 on: January 14, 2022, 03:30:28 pm »
Hi Pamela,

I thought I would send you my numbers. It’s very interesting how varied
the numbers are for everyone. My E shot up and I’m not sure why, I don’t
really feel any different. Anyway my doc wants to test again in a month,
so we’ll see.

Month 0
July 26,21 first day HRT
E-28
T-342
3 month 10/26/21
E-36
T-379
5 month plus a week
Just received result yesterday
E-853
T-248

So as you can see E went nuts,😂
I will send in next months numbers.

Thank You so much,
Sheila

Thank you Sheila for these Blood Test results which I truly appreciate.

As this if your first set of BT results, could you please confirm:

1. That these are US results please. Obviously most Members are from US but other countries (Canada, Australia, UK where I live) use International Units.

2. Please check your stated January E result of 853 which is way up from October E result of 36.

Thanking you for your kind help.

Hugs

Pamela xx

Offline Ginger Tea

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Re: Comparison of our HRT Blood Test Results
« Reply #456 on: January 14, 2022, 04:22:37 pm »
Hi Pamela,
Those are US numbers.
Yes, I was blown away by the E number from this test.
I have a new dr and I asked her several times if this was correct,
and she said yes, but let’s retest in a month. So we’ll see, I think
the test was messed up some way, IDK.
Anyway, I’ll let you know how next months test goes.

Thank You,
Sheila

Offline pamelatransuk

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Re: Comparison of our HRT Blood Test Results
« Reply #457 on: January 14, 2022, 06:00:00 pm »
Thank you Sheila for all your information.

Your T results convert to 12, 13 & 9 (Intl) respectively.

Your E results convert to 103, 132 & 3131 respectively.

Good luck for your February BT.

Hugs

Pamela xx


Well, well I sent this at precisely midnight or 6.00pm on website!

Tags: Cycling HRT