Yes, still butting in. The only way for you to be missing progesterone receptors is if there were no gene for it. Even if it is on the female chromosome (X), there is no way you could not have it unless you were born with a rare genetic condition in which that gene did not work.
According to current knowledge in genetics, males cannot possibly be lacking any receptors for female proteins, or female protein genes. So he is an idiot.
Well like you said, they can if they have a rare genetic disease.
Like, giantism is caused because of lack of estrogens for whatever reason, or excessive growth pattern or even excessive growth hormone.
A variation of giantism (usually in males only as in females the chance is reallllllllllly low) is a missing or broken gene of the estrogen receptors.
If that is the case, estrogen pills/injections do not stop giantism and the bones continue to grow until the material bone is created from is consumed, that is called "proliferative exhaustion".
Estrogen actually causes "pre-mature" proliferative exhaustion, then again - since this premature proliferative exhaustion is normal, it is the other proliferative exhaustion which is considered abnormal
Maybe the world had giants after all!
I'd like to point a thought which came across my mind for a bit.
XX has double the receptors for progesterones and estrogens.
It doesn't explain why the breasts grow better, just in case someone came to that conclusion.
As we can see trans from young age have normal growth with normal regimes if not even lower.
We should have more receptors than the estrogen that can flood them anyways.
Another thing to consider is the "disease" that causes giant breasts, I think recorded up to 74 pounds per breast, it's caused by either a lot of estrogen in the body or over-sensitivity.
So apparently increasing amount of estrogen should help, but even better is find ways to increase estrogen sensitivity.
You probably heard of insulin insensetivity and sensitivity or even androgens.
It is well known certain foods, chemicals, lifestyles and etc increase and decreases sensitivity for different compounds in the body.
If anyone feels like it, we should look for ways to increase estrogen sensitivity and post them here or in a new thread over the hormone therapy boards.
Anyone is interested?