I try not to be offended about show whose sole purpose seems to be to offend people. South Park is very hit/miss on this, there are a few Ms Garrison episodes I just don't care for, but some of them (the 300 parody, and the one with Dawkins) are hilarious.
I haven't heard anyone complain about Venture Brothers, which does the same thing. Is it just that the show is less well known?