Ask any (predominantly younger) surgical-menopause natal-female...
Many 'normal' menopause women have very few syndromes and eventually get over them too.
So in any case it will differ some from person to person.
Over the long term you will get fat as your body will try and use body fat for E production, you will start to loose bone density after some years for sure, you will get plenty menopause syndromes like night sweats, hot and cold flushes, will feel not at your best, might get greasy skin and hair, might loose scalp air, have heart palpitations, dizziness, headaches, urinary frequency, etc. etc.
Or... hardly anything of the above.
Axélle