I wonder this too, my shoulders and back and upper arms are my only "Problem" area that I just hate, they are a tad too big and bulky looking in female clothing items, I have to be VERY selective in my clothing choices, I just started a full-dose HRT regimine about 6 weeks ago however; so I know that it WILL take some time, but I pray I see some nice differences from before HRT and on HRT, I heard it takes a while though for upper body male muscle to melt away to look more feminine, I just hope it DOES at some point!