I think a good analogy is the boiling a live frog one. If done slowly the body doesn't react in a way we don't want it to. If I was going to double my E, I would be doing it over a period of a month or so, not just start taking 2X the dosage the next day. I think too many people want to try to force this second puberty to happen over a period of 6 months to a year. My goal is to take the minimum amount of meds that produce results. If it takes 2-3 years to get the "final results", that's more of a normal time period for changes like this to occur. I don't think the "shock treatment" plans are a good idea.