I have tried both injections and the patches, and I prefer the patches, I use a patch and low dose of the oral. and im a few months into being on full doses of both, endo's have many ways of going about hrt. Because I was a smoker. my endo put me on the patches to give me the estrogen, and put me on the oral to boost the estrogen but to also get the bi product sex hormone binding globulents. (totally butchered the spelling XD) only reason I like the patches also is its easy to remenber when its time to change them, I forgot when it was time to inject myself alot.