Great info Jamie! As for the relative safety of estrogen and potency I think pellets go first, then injections, then transdermal and then 17b estrogens, like estrofem. Premarin would be last. I know one girl who took it and had all sorts of side effects and luckily switched to estrofem. But with injections you don't get much consistency unlike sublingual b17s and transdermals don't work as well cause of their ability to stick. I think injections and pellets are good especially for those with liver problems. But I heard that sublingual b17s don't effect the liver much at all either and are just as consistent as pellets. Most can't afford pellets however, and they are prob are a tad better since of the steady dose and the fact you don't have to take a pill twice a day and you avoid all liver problems, which would be good for trans women who may have a bad alcohol history from their GID. I think ethinyl estradiol is actually the one that produces fastest results but also causes DVT big time.
I just hope and soon that everyone who has GID can get access to HRT regardless of health problems. But if you want something bad enough you'll work 16 hour days if necessary. I don't have to work that much but if I had to I would. I read people with AIDS are a lot to transition so I maybe we are already there lol