Personally speaking, there is only one time I have ever even considered it. And that was before I realized that I was in fact, female.
I had spent my entire life trying desperately to be what I had been told as a child and young adult that I was meant to be...a man. It didn't feel right, and in fact I was anything but your typical male, but I tried hard because I thought that it was what I was supposed to be.
I was married for over a decade, had a Son, and then my marriage was destroyed due to my lack of libido, which stemmed from sexual dysphoria.....it felt like I was trying to use the wrong tools for the job, so to speak. Eventually the intimacy stopped all together, which of course drove my wife into the arms of another man. I couldn't blame her.
I tried dating after that, with disastrous results. I wondered if maybe I was gay, and tried that for a bit, but that wasn't right either.
I became romantically involved with a close friend, and we tried to make a go of it for a while, but again...I could get aroused, but as soon as the act began, I lost it. She moved on as well.
I sank deeper into depression than ever before. I didn't know WHAT I was, or what was wrong with me. I was lonely, scared that there was some medical explanation, afraid that I would be a sexless thing for the rest of my days. I lost my job, and pretty much everything, and just sat in my chair, staring at my computer screen, waiting for the end. And considering hastening it along.
But that is when I finally dared to ask myself....if maybe I might just be the wrong gender!!! And of course that was it, and the revelation changed my life in such drastic, and positive ways that it was dizzying for a while.
But yes....I can think of a few reasons that a trans person might consider ending their lives. From the horror and confusion that gender dysphoria can cause, to potentially losing one's friends, family and job after coming out, to the seemingly overwhelming task and monetary cost of transition itself.
This is one of the reasons that communities like this are so important. We have to help each other through these times. We have to be there for one another, emotionally, and though the sharing of knowledge and resources. United we stand, after all.