Quote from: Keira on July 05, 2007, 12:33:32 AM
Try dutasteride, you are very very sensible to DHT and it needs to be cut off as much as possible.
Your T will diminish, so T -> DHT ---> Anti-Androgen blocks receptor
-> DHT ---> Receptor not occupied by anti-androgen
A Anti-Androgen will diminish, an anti-androgen will catch most of the DHT before it reaches the receptors but not all.
So, you need to diminish the conversion of T to DHT, propecia diminishes that about 70%, dutasteride diminishes much more (can't recall the exact number).
Dutasteride blocks 90% of all DHT, and 56% of scalp DHT and both types of DHT. (Dutasteride .5 mg drops it to 90% blocking of all DHT after 2 weeks).
Finnestede blocks 70-80% of one type of DHT and 36% of the scalp DHT of that one type. It also takes longer to get to that level.
Only problem, both types of DHT can cause the hair loss. So proprecia does not work for everybody. At the same time Dutasteride does not work for everybody either.
Anti-androgens block both T production and DHT receptors, but not necessarily the T to DHT production itself. For me because of the fact I did lose so much hair going into HRT I have basically put a DHT blocker in the HRT mix. Stoping all production of that terrible chemical was as key as blocking T, if not moreso because while I have low sensitivity to the effects of T and low T, I have excessive sensitivity to DHT.
I wish I could say I have been seeing results but the reality is that may take some time before anything happens and there has been a ton of damage done.
Also the person writing. Don't worry so much about the effectiveness of HRT. Its a silly worry we all have. You are going to be fine.
PS There is a 50% of all TS have full hair recovery from HRT. The thing is the younger the age, the more likely the recovery because the more likely the micro-hairs (they look like peach fuzz) still exist. I could go on, but the average is probably higher than 50% for TS under 30, and may be higher under 40. The age range background of the study was not detailed as it should have been.
Sadly they have not done studies for those who use a DHT blocker as an additional anti-androgen. I would not be surprised if it pushed up that 50% number significantly.