I'd definitely talk to your doctor, Shane. What gauge needle are you using to inject and where are you injecting? I use a 23 gauge (I hope that isn't violating the prescription rule, I don't think it does, if it does, pm me) needle and inject in the upper quadrant of my butt. I'd also be cognizant of the desired effect of the E on you. Shots tend to work a little quicker I think, but I'm not sure 🙂 Hope you are doing well!