The only problem I see with taking Spiro and no estrogen is that your T will reduce without replacing with E so you might experiences symptoms associated with male andropause or female menopause, not enough sex hormones. Hot flushes, heavy sweating, insomnia, irritability, depression, cognitive impairment, bone loss over time, etc. It depends also on how much Spiro you are taking, lower doses shouldn't be that bad but higher, those typically used for transsexual women could be problematic.
Also, be sure to drink enough spring water, avoiding mineral water, fruit juices, energy/sports drinks, sodas, anything that contains too much potassium, eat salty if you feel like it as you'll lose a lot of sodium (spiro is a diuretic), avoid salt substitutes though cause they contain a lot of potassium. Taking Spiro with food will increase its absorption and increase bioavailability while also reducing possible stomach irritation.
Just wanted to make you aware in case your doctor had forgotten. I just want you to be safe.
