You'll probably be more thirsty than usual and crave salt more so be sure to drink plenty of natural/spring water and as much salt as you want. Moderate your intake of diuretics. Avoid high potassium stuff like fruit juices, sodas, mineral water, energy/sports drinks, salt substitutes, bananas, potatoes, etc. This will help with the dizziness, cramping, dehydration that might occur with Spiro. If, despite taking these precautions, problems persist and you really don't feel good, then contact your doctor immediately. It's best to start low with Spiro and gradually increase, over several weeks to give your body time to adjust.