Will artificial ovaries be possible for us non cis?

[Paige0000]

Hi everyone I've just been looking into the future of artificial ovaries and what they will be able to do for future women. I am hopeful they will also be usable for us noncis women for they will create a great alternative to hrt and possibly allowing us to produce our own eggs which to use for creating our own natural children.
Obviously not via pregnancy but through use of a surgate.

Do you think this will be possible in the near future? I.e 5-10 years? I hope so because the possibility of having my own children created by my egg would be just...well words can't describe really.

One can always hope xx

[allisonsteph]

I think it will be possible in the future, but not in the next 5-10 years. I can't imagine there being enough profit in it to justify the expense of the research that would be required if helping trans folks is the only goal. Now if they were trying to find something to help infertile cis women conceive and discovered that it would work in an "off label" application, then I can see it happening.

[Jessica Merriman]

Biggest problem right now with artificial genetically produced are how they will initiate DNA replication and who's to use for the original blueprint. I don't see anything being ready for 15-20 years, but in all likelihood much longer based in a large part what Allison mentioned, cost factor. There is just not a demand right now. Transplants have been attempted as well as Uterine transplants, but the rejection factor hasn't been solved. I believe the last Uterine transplant into a MtF test subject were rejected 4 days Post Op.

[Randi]

You are talking about two separate functions that could be replicated. 

It is already possible to create both sperm and egg using donor cells and taking the DNA from skin cells which have been changed in to stem cells.

In other words it is possible, at least in mice, to create either an egg or sperm with the desired DNA regardless of the sex of the patient.

http://www.healthline.com/health-news/tech-researchers-make-sperm-and-eggs-from-adult-skin-cells-082613

The other function is to secrete hormones.  This function can be handled by periodic injections or pellets.  I think they have implantable insulin pumps for diabetics. 

http://www.diabetes.org/living-with-diabetes/treatment-and-care/medication/insulin/insulin-pumps.html

Would this really be better than pellets or periodic injections?  This machine wouldn't actually make hormones, just release them on a regular basis. It would obviously require periodic refilling, and recharging of the power source.

As far as transplanting donor ovaries, they have been trying that for nearly 100 years.  Many men received transplanted "goat glands" back in the 1930's.  Some died.  Google up "John R. Brinkley" and you'll learn all about that.

Regards,

Randi