I use to be 325 pounds, alcoholic did drugs and smoked. I had chest and neck pains since I was 18 almost continuously. I was on the highest oral meds and my sugar was 145 fasting and they wanted to go to injections. I had a diabetic ulcer with bone exposed. I had 3 or so x-rays and was taking cipro antibiotic for a long time. My legs were dark and my feet darker and feet joints dark, I was 35 years old with a 6 or 8 month old. I went to 180 by exercise and diet change. I stopped drinking and drugs and my diabetes went under control. I have been 5.0 to 5.3 hA1C since. I still had chest and neck pains though.
HRT at age 50. I have had a hA1c of around 5.2 for 13 months and my PA said I no longer have diabetes and I weigh 214 pounds ( I am exercising to get to 180). I still have diabetes because I still have a bit of vascular issues on my shins (brown) but improving since the addition of progesterone but that may be coincidence. Further, my eyes get blurry if I eat the wrong stuff and I feel like crap. Although, 3 days after I started HRT I never had another chest or neck pain. Also, I noticed the tingling feeling in my fingers went away and my feet felt better by still have some foot nerve damage, but improving. I had hand and foot tingling since 11.
So for me I think I caused a lot of damage to my body that has taken many years to repair. Sad but at 52 I feel and am in much better body condition than at any time in my life from 11 to 50, I just need to drop a few pounds. I think HRT, therapy and Susan's has help me phenomenally physically and mentally. (just my 2 cents. )