How long does it for estrogen to go into your system

[AlexisB]

Just curious from when I take my estrogen pill how long does it take to go into my system and affect my estrogen levels?

[Ms Grace]

I imagine it wouldn't be more than an hour or two at the most...?

[Dee Marshall]

Early on, I felt it, strongly, within 5 minutes. Now, three weeks later my levels have built up to the point that I don't feel that rush, or a pre-dose letdown. I do have fairly high skin permeability, so it might well be getting into my bloodstream through my stomach lining.