In my first two months on the estradiol spray (which I have since discontinued because it was too weak), I noticed some fat shift from my waist and abdominal area to my butt, causing proportional spreading of the waist and hip measurements. Also in those two months, I noticed a shift from the sides and back to the chest. Both changes became evident within 3 weeks and continued until 2 months had passed. My weight did not change during that time. However, I admittedly did a rather excessive amount of walking then, some of it in hilly areas. I seem to require a combination of estradiol and physical activity to see any redistribution. When I am inactive there is no improvement and sometimes it even goes back the wrong way!