As I move through transition, some of my old interests remain but many I began to realize were part of my attempts to be "macho". And new things are taking my interests as I move forward.
I had a great love of music when younger and still fighting with myself over my sense of self, then that got buried as I moved into adulthood and was made worse with hearing loss as an adult. Now I find myself returning to an interest in it and finally learning what I can and cannot listen to and enjoy despite that handicap. Without transition, I don't think I would have even tried.
But as others have noted, depression might in play here too. And the medications may not have helped because it's depression at your GID so until you tackle that, you may not be able to shake it.
If you are seeing a therapist, I'd start discussing gender identity issues. If you are not, I'd advise starting. Be honest, open, and listen. A good therapist will make you think, make you remember things you've wanted to suppress, and help you face certain things about yourself. But that only happens if you can be honest and open.