My doctor only does subq injections, so thats what I have been using since starting T 10 months ago, the needle is small and it pretty much is painless, I don't think im on a high dose of T, avg I think, i like the results its given me, my T does say for IM use only, but it works fine with subq shots, I believe subq is suppose to be cheaper also? not sure since I never had to do IM shots.