Doing some math

[Amy1988]

Ok so I read that the liver metabolizes about 30% of the pill form estradiol.  So if a person takes 2mg then by my calculations that would leave 1.4mg that survives the liver?

[KayXo]

Bio-availability from pills is typically, on average, 5% so that only 5% of the estradiol swallowed will make it to the blood. I can PM you the various sources that cite this.

From 2 mg, you get 0.1 mg estradiol, similar to the 0.1 mg patch.

[Amy1988]

Ok so I read that the liver metabolizes about 30% of the pill form estradiol.  So if a person takes 2mg then by my calculations that would leave 1.4mg that survives the liver?

Please send PM

[ImagineKate]

I take it sublingually to avoid the liver pass.

[Amy1988]

Bio-availability from pills is typically, on average, 5% so that only 5% of the estradiol swallowed will make it to the blood. I can PM you the various sources that cite this.

From 2 mg, you get 0.1 mg estradiol, similar to the 0.1 mg patch.

What is the bioavailability of .6 mg estradiol gel?