Questions About Progesterone

[Laura_7]

There are studies showing it prevents Testosterone to DHT conversion (only bioidentical progesterone).

Progesterone typically does not cause breast growth, but merely temporary swelling that subsides when the P level drops.

Some people say it might help some with the structure of breast tissues.
( development of the lobules and alveoli in the breasts)
Some people reported this after being already some time on hrt.

[KayXo]

The one study that showed significant inhibition of T to DHT by progesterone was in the presence of extremely high levels of progesterone that do not naturally occur in humans, even during pregnancy.

[Laura_7]

The one study that showed significant inhibition of T to DHT by progesterone was in the presence of extremely high levels of progesterone that do not naturally occur in humans, even during pregnancy.

This one ?

ncbi dot nlm dot nih dot gov/pubmed/1828548?dopt=Abstract

hugs

[KayXo]

YES! this one. Progesterone levelsin this study were 10(-4) mol/l or after conversion to ng/ml, 31,450 ng/ml compared to peak levels reaching at most 400 ng/ml during pregnancy. On typical doses prescribed to us, we can hope, at most, to reach 50-100 ng/ml for a few hours and that is stretching it, in those whose metabolism is slow or impaired.