HRT Questions

[missymarieme]

I  have my appointment for HRT set up. I was reading an article in cosmopolitan that what the doctor's concern the most is liver conditions and blood cots. I was wondering if anyone knows how much higher risk are the chances for someone who has had pervious blood cots.

With love, caring and understanding, Melissa Marie

[Laura_7]

Hello and welcome 

Concerning clotting there are different factors...
smoking might be one... so quitting might be helpful...

most straining on the liver and causing clotting factors is oral intake...
bioidentical estrogen should be preferred imo because there are no further non identical components...
then sublingual intake which is supposed to bypass the liver with intake...
its possible to break the daily dose down in a few small doses so levels are more steady...
then patches...
then injections and implants.
Injections and implants are considered the most safest... implants also make for steady levels which might help avoid mood swings...

some people with risk factors might take a daily very small dose of aspirin...
just talk it through with your doctor because it might make stopping bleeding from wounds a bit more difficult...

another idea might be bioidentical progesterone...
it might complement estrogen, help with mood and even out some side effects, it also has some anti androgenic effects.
As said, talk it all through with your doc.

[brenda w]

I know i have read post regarding implants. i did a search and found the statistical results to be not consistent and insurance companies consider it experimental. only to be had from a compounding facility.patches would be the most likely route for you to take. As previous poster stated smoking is big red flag. my doctor has me low dose and will not up it until i quit, and i have no clotting history. but also age can be a factor.

[Joi]

If you have had clotting problems, the safest is likely patches.  I use them.  No  clotting problems, but the age factor + little to no impact on the liver and kidneys.

[Laura_7]

I know i have read post regarding implants. i did a search and found the statistical results to be not consistent and insurance companies consider it experimental. only to be had from a compounding facility.patches would be the most likely route for you to take. As previous poster stated smoking is big red flag. my doctor has me low dose and will not up it until i quit, and i have no clotting history. but also age can be a factor.

Well concerning convenience and stable release there is no comparison to implants.
There might be different doses released per pellet, for unknown reasons. But endocrinolohy is not exact science, its adapting to the reactions of the customers. Adaption is quite easy.

Well with patches its the same... skins are different.

In countries like Australia its a standard. And concerning coverage, its possible some come around. Testo pellets for trans men begin to be covered.

Concerning patches you might have a look here:
https://www.susans.org/forums/index.php/topic,189624.msg1687810.html#msg1687810

There is also compounded topical gel.

And concerning implants here:
https://www.susans.org/forums/index.php/topic,192044.msg1713877.html#msg1713877

Another idea might be to talk with the doctor about additional bioidentical progesterone.
It might compliment estrogen, even out some side effects , help with mood and have some antiandrogen effects.

[Deborah]

My endo told me they had never really seen anyone have liver problems with HRT.  That probably assumes your liver is healthy to start with.


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