I am three months on HRT, and while I have had a noticeable change in fullness on both sides, the left is definitely a little bigger than the right. I have experienced no pain or tenderness, and my areola region is no different, but my nipples have gotten bigger.
I was actually quite surprised that anything has happened (I'm 58!), and it really wasn't in my game plan. I started out on a very low dose in July of just spiro and finasteride, and my endo added fairly low dose of E in August. He bumped up the E and spiro this month, but the changes had already taken place.
I still present as male at work, and I have some serious man boobs now. I actually bought a sports bra, and may have to start wearing it under a t-shirt with a loose shirt.