Estradiol Injections

[KayXo]

I've read and know some who take progesterone  for breast and nipple development . I've never found anything conclusive that it's necessary . I brought it up with my Endo , but she thinks it's not needed. Might try and discuss with her again.

Studies have unequivocally shown that progesterone stimulates certain structures in the breast. There are other benefits, mentally and physiologically, as well, for some as reported by several studies.

Hello Everyone, My SRS surgeon who can also do HRT told me that injecting Estradiol Valerate in the rear increases it's size.  So in the butt it goes, alternating cheeks every 7 days.  Seems to work or at least hoping it does.

It's not because estradiol is injected in that area that the butt will increase more. Estradiol injected intramuscularly, whether in the shoulders, quads, butt will have the same effect because it will be absorbed into the blood and circulate all over the body, not preferentially to one tissue because it was injected there. Estradiol, in general, increases fat deposition in the glutofemoral (butt and thighs) region. I can attest to that effect, progesterone seems to accentuate this.

I inject in butt only and fat deposition has increased in both butt and thigh area. So, no point in injecting in one area vs. another to preferentially increase deposition in one specific area.

Well it should be bioidentical progesterone... synthetic one does not have the same effects...

Bio-identical progesterone is also synthetic as it is produced in the labs by man BUT its molecule is identical to what is produced in the human body so this is why it's said to be bio-identical. Premarin is NOT synthetic as it extracted from pregnant mares' urine (in nature) BUT contains many forms of estrogen not found in the human body so is not bio-identical. I think it is important to make that distinction.

Bio-identical progesterone and all other progestogens have the same effect on breast tissue (growth) BUT effects may differ in other areas and also in terms of risks (i.e. breast cancer).

It helps with development of breast ducts...

Studies have shown that estrogen promotes duct development/enlargement making breasts conical while progesterone promotes lobuloalveolar growth (milk glands) making breasts rounder and fuller. They both also increase fat deposition in the area.

[AprilV]

Well it should be bioidentical progesterone... synthetic one does not have the same effects...

well in cis women its also present. It helps with development of breast ducts...

livestrong.com/article/319391-the-effects-of-progesterone-on-the-breast

Estrogen is the primary hormone that stimulates breast growth during puberty, but progesterone is required to convert the female breast into a milk-producing organ. Dr. Carol Lange reports in the article in Steroids that progesterone, along with other hormones, stimulates development of the mammary glands in the breast.

Many people report a more rounded form instead of a conical one...


hugs

Thanks for the information.  Now to convince my Endo. I would hate to have to find another Dr. I like her alot and took 3 months to get in and see her.

[KayXo]

Ask her what's the worse that can happen, to test your blood values, etc. To just give it a try and see and if anything out of the ordinary occurs, to stop it. Studies have not found an increase in breast cancer with P, nor any risk of increased clotting, androgenicity, etc. It's important your doctor knows the difference between bio-identical P and other progestogens which have a bad rap, like Provera (medroxyprogesterone acetate).

Just think (and tell her this) for a moment....women have progesterone coursing through their bodies for decades, very high levels during pregnancy also flooding the fetus and progesterone is sometimes prescribed to pregnant women for miscarriage/premature labor, sometimes in quite high doses. Pregnancy is often not a one time affair neither!