I recommend calling your physician. I am no medical profession and I do not think many of us are qualified to answer your question safely; however, I am taking Estradiol, and my paperwork gives me a list of things I should call my doctor about (when Estradiol was prescribed to me):
"... Signs of liver problems like dark urine,
feeling tired,
not hungry,
upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes. Chest pain or pressure. Shortness of breath. Coughing up blood. Swelling, warmth, numbness, change of color, or pain in a leg or arm. Very bad headache. Very bad dizziness or passing out. Change in strength on 1 side is great than the other, trouble speaking or thinking, change in balance, or blurred eyesight. Very upset stomach or throwing up. Very bad belly pain. Back pain. Bulging eyes. Change in how contact lenses feel in the eyes. Change in eyesight..."
I listed the other things in case you may be noticing other symptoms. Even if these are the only things you are noticing... I still recommend calling your physician. It's better to be safe than sorry, and the worst that can happen is that they say it is no big deal and you are well off -- that's a pretty good deal for you
Aside from Estradiol, if you were to say this was Spiro, then I would say these are more normal symptoms; however, you were pointing out specifically to the change in estrogen, so I am thinking you should call your physician for medical advice.
Good luck, and get well!
