I'm trying to find the reference it was by Laurens et al and I have posted it before.
It was a survey in the UK and Europe of around 1000-2000 transgender men and women. From memory, women had a slight increase in cardiovascular disease compared to natal females. There was a very slight increase in Ca breast compared to natal males.
Transmen had no significant increase in disease levels compared to natal males. They had a lower incidence of Ca breast compered to natal females (probably due to chest surgery and removal of oestrogen and not having had children).
I recall the conclusion was that gender reassignment in transgender males had no increase in morbidity.
I do know that the greatest risk to men is obesity driven issues. Probably true for all genders at the moment.