Quote from: Luna Star on March 03, 2016, 06:53:53 AM
Not to pop your bubble but you do know how gene therapy works right? For that to even work we would have to be able to change all the cells in our body from an xx chromosome to an xy and vice versa.
It's not necessary to do any genetic alterations, because your sex isn't directly determined by genetics. Instead it's determined by what hormones are present during a critical period that starts about 6 weeks after conception and ends a few months after birth, and is later reinforced and maintained in adulthood by hormones as well.
The Y chromosome only contains a very small number of genes. There's the SRY gene, which directs your undifferentiated gonads to turn into testicles, and there's a few dozen other genes on it that are mainly involved with spermatogenesis. Outside of testicular tissue, the Y chromosome doesn't appear to do anything at all. It's the hormones produced by the testicles, not the Y chromosome, that cause male development to occur, and without those hormones, development occurs as female instead. There are certain medical conditions proving this to be the case (I've included some examples in the link at the end of this comment).
In other words, apart from the cells in gonadal tissue, all the cells throughout the human body appear to be effectively "gender neutral", and will quite happily function as either male or female cells, depending on what hormones are present. So no gene therapy is necessary, just taking the appropriate hormones for several years is enough to change the metabolism of all the cells throughout your body to match your chosen gender!
https://www.quora.com/What-causes-a-person-to-be-transgender/answer/Hugh-Easton-1