HRT T blockers Spiro vs Androcur?

[RUBYYY]

Hello my lovelly girls i hope you all will have a wonderful weekend
As i am from Europe in our country the endro prescribes you first a t blocker wich can be spiroctone or androcur (  Cyproterone acetate )
Now i read many say CPA is much better for the results but is also more dangerous, has anyone expirience with Cpa and what is really the diference, maybe the topic was allready talked about that for i am sorry but im new and didnt saw all the posts
Just want to know what to be carefull of if getting one of them, and the diference effects, i know cpa is not aproved by fda in USA, so i think european girls can help me more during having more expirience with  Cyproterone acetate...
In the end what i will get i keep you up with that
hugs and kisses


NO DOSAGES

[KayXo]

I personally prefer spironolactone, Lhrh agonists and bicalutamide to cyproterone acetate due to potential side-effects.

[April_TO]

I am currently on CPA on a lower dose and it seems to be working perfectly for me. I have seen rapid feminization on the 3 months that I have been on it compared to a year and a half of Spiro. Spironolactone on the other hand affected my kidney function. I always felt a pressure building up below my navel - little did I know it was making my kidney work extra hard.

With the right dose and proper monitoring from your doctor, I would suggest CPA.

[KayXo]

Aren't the kidneys located well above the navel?

[Lebedinaja]

I always felt a pressure building up below my navel - little did I know it was making my kidney work extra hard.

same for me with CPA. dangerous?

[April_TO]

same for me with CPA. dangerous?

I am not quite sure if that is related to CPA - you may want to check with your MD. For me, it was definitely Spiro causing all the nasty side effects. I wouldn't go back to it even if you pay me a million dollars

To each their own - hope you find what works for you.

[RUBYYY]

I was by my Endocrinologist and he said HE DONT LIKE ANDROCUR and perffer to his transgender feamle patients SPIROCTONE... So i will get spiro, i think they give Cyproterone acetate only if spiroctone is not tolerated, IN EUROPE IT IS IN USE( germany,austria ect...)
Some people say effects from androcur are better ( changes in body and face) but mentally and side effects are worse then spiroctone..
I hope spiroctone does the same end result as androcur

[Lebedinaja]

I was by my Endocrinologist and he said HE DONT LIKE ANDROCUR and perffer to his transgender feamle patients SPIROCTONE... So i will get spiro, i think they give Cyproterone acetate only if spiroctone is not tolerated, IN EUROPE IT IS IN USE( germany,austria ect...)
Some people say effects from androcur are better ( changes in body and face) but mentally and side effects are worse then spiroctone..
I hope spiroctone does the same end result as androcur

well one thing that I can tell you, CPA, Androcur side effects are quite bad for me. Depressions!

[Richenda]

We all react differently to different drug regimes. One girl's medicine may be another's poison. For example, spironolactone nearly killed me. I also reacted very badly to bicalutamide which I do not consider as a result to be 'safe.'

Remember, virtually all these drugs are prescribed as secondary to their primary purpose which may be as diuretics or cancer treatments etc.

Make sure you are monitored is all I can say.

I've personally had enough of AA's to the point where I'm having an orchie next month.

[Lebedinaja]

so after some research on the stuff I am actually taking everyday, CPA does have some more risks in general, as far as I know now. It's not meant for long term treatment of transgender patients! so if this is the choice (like it has to be for me) then it's good to have the srs or sth else not too far in the future.
I heard that CPA is more effective and can block T waaay longer and a bit better probably but yes, that's everything I can say without leaning out of the window too much

[April_TO]

Actually both have side effects they just impact more or less a different organ. Spiro will hit your kidney big time and CPA can be hepatoxic when taken on higher doses. The assumption that SPIRO is safer than CPA is long gone myth. Just like Richenda said, you pick your poison and hopefully it works out for you.

Bottomline, any drug/s you take can potentially kill you. Just make sure you have proper medical monitoring.

so after some research on the stuff I am actually taking everyday, CPA does have some more risks in general, as far as I know now. It's not meant for long term treatment of transgender patients! so if this is the choice (like it has to be for me) then it's good to have the srs or sth else not too far in the future.
I heard that CPA is more effective and can block T waaay longer and a bit better probably but yes, that's everything I can say without leaning out of the window too much

[KayXo]

Spiro will hit your kidney big time

Rare occurrence of kidney problems on spiro.

The assumption that SPIRO is safer than CPA is long gone myth. Just like Richenda said, you pick your poison and hopefully it works out for you.

I consider, based on the studies and anecdotal evidence I've come across in the last 12 years, that some anti-androgens pose less risks, CPA being the worst, then Spiro, bicalutamide and finally LhRH agonist.

Bottomline, any drug/s you take can potentially kill you. Just make sure you have proper medical monitoring.

The potential to "Kill you" is extremely low, if used properly and one is monitored. Some drugs appear to have more side-effects than others, all drugs are not made equal and I agree, response may vary across individuals.

[April_TO]

LOL so are you saying that in complete absolute truth than no meds has a possibility of killing you.
As you have said in the past, you are not a medical doctor and claiming that one drug is better than the other is actually stepping over your boundaries as a lay man.

I don't mean to be rude but until the medical community can come together and endorse an AA made for us, it is important to be objective in your recommendations.

Be neutral, it not anyone's job on this site to recommend which one is better than the other. That is between a patient and his/her medical doctor.

Rare occurrence of kidney problems on spiro.

I consider, based on the studies and anecdotal evidence I've come across in the last 12 years, that some anti-androgens pose less risks, CPA being the worst, then Spiro, bicalutamide and finally LhRH agonist.

The potential to "Kill you" is extremely low. It's important to remain objective and not exaggerate.

[KayXo]

LOL so are you saying that in complete absolute truth than no meds has a possibility of killing you.

I stated the potential was extremely low, if certain conditions are met.

As you have said in the past, you are not a medical doctor and claiming that one drug is better than the other is actually stepping over your boundaries as a lay man.

I'm simply expressing my opinion and clearly state I am not a doctor. We are exchanging ideas and we may not always be on the same page. So be it. In the end, the doctor decides what is best for the patient, regardless of what is written on this forum.

I don't mean to be rude but until the medical community can come together and endorse an AA made for us, it is important to be objective in your recommendations.

I don't recommend. I'm sharing my point of view.

Be neutral, it not anyone's job on this site to recommend which one is better than the other. That is between a patient and his/her medical doctor.

I believe I am quite objective and only state my opinion on the subject matter. Others may disagree, doctors may even disagree amongst themselves.