My tiredness went away after 2 months to 1 1/2 years. I started getting energy and strength after the 2 months. The above advice from Deborah is a must here. But in my case, my painful neuropathy flareup over the past 4 plus years put me on nerve pain meds, thyroid, and 8 months of IVIg treatments requiring a visiting nurse. After all of this was done I was put off of the E due to edema of the feet which is indicated, and then off of Spiro to rest my system for a few months. The above treatments for the neuropathy put me in bed more than up due to a narcoleptic reaction to the extreme pain as these painkillers did not even touch the pain.
Now, I'm off of everything and my energy levels rising now have a sharp edge to it. Some tiredness remains as residue, but I am still coping.
Joelene