High DHEA sulfate and poor feminization

[KayXo]

Well, I just had my DHEA-S tested again and it went up dramatically to a record 550mcg/dl! That is three times a typical female level and borderline high for a male, which my endocrinologist admitted. He told me there is no way to reduce the level except corticosteroids, which are harmful because they mimic cortisol, which I already have a high normal range level of. He said the bicalutamide should block it even at that high level

DHEA-S is not an active androgen (a reservoir) that needs to be blocked (doesn't trigger receptors) and serves as a precursor for the potent androgens such as testosterone and DHT. Did you measure T and DHT? Those levels are more relevant and even then, it depends on your body's sensitivity to those hormones since a high level may not produce much androgenic effect in a person who is not very sensitive. I think what matter most is if your body is masculinizing, feminizing or what? Those are the things one needs to look at, I think.