I can support the "not feeling aligned with a strictly gender-segregated cisgender society". For me, there are two components:
The body and the desire to make it more "fitting", but this is not related to the gender role; and the gender role, which is not necessarily related to the body. In my case, I had both the desire to change some properties of my body, and I couldn't live with the male gender role anymore. The problem is that I'm not female either, so it ends up being an alien who doesn't fit in gender-segregated spaces. So I avoid those absurd spaces whenever possible.
It makes communication more difficult (pronouns etc.), but it also gives a chance to see and learn things most people are not aware of.
Personally, it also means discovering the true self and learning to question social behavior models, especially in relation to gender. There are problems which came with it (I knew it since I was in my twenties, funnily enough I didn't enjoy playing with pink dolls as a child, but assumed the role which I was assigned without resistance), but it can also make much more happy when you realize that your body is truly yours, and when you can feel the inner freedom of not having to play a certain gender role, but just to be yourself.