I went from taking two every morning to splitting one at about 8 and the other at about 9PM - my bedtime is generally about 10-11. That meant a change from getting up about once per night to twice. That made me go back to once again. My prescriptions says once.
My doctor says it doesn't really matter because of the half-life of the med, but i don't know i may go back to twice.
Decisions, decisions. (or in this indecisions, indecisions)