It's been used in women, old and young, in Germany, to treat osteopenia and poor breast development. Side-effects were minimal, women responded positively and some were "eager to continue". To treat the risk of miscarriage, only certain progestogens are prescribed as this helps maintain pregnancy. In my personal opinion, it's a good treatment but estradiol needs to be high enough to compensate for the mild anti-estrogenic effects of progestogens.
I am on a high dose of EV taken IM and oral progesterone. My health is good, I feel pretty good but breast growth is poor.