I just picked up my patches today and will be starting them tomorrow. I read the leaflet that was in the box with the meds, and it says that you are supposed to peel one side of the patch and apply to your skin, and press on it for a few seconds; and then peel the other side of the patch, press it on your skin for a few second, and the press the whole patch against your skin for several more seconds. You may be doing this already, but I thought I would mention it just in case. I considered the pellets, but decided against them because there is a risk of infection every time you have them inserted, and if they are causing problems it's a hassle to try to have them taken out; and the provider wanted to wait a month after implanting them to check my hormone levels, so I would have no way of knowing if my levels were extremely high during that time, and the reason I wanted pellets in the first place was for consistent estrogen levels, so my levels could have been over a thousand for the first couple of weeks and then started dropping, and by the time my levels were checked at 4 weeks after insertion could be in the 200-400 range and I could have been misled into thinking that my levels were 200-400 all along. No thank you.