I currently take it. Because my Dr. gave it to me to reduce my habits of doing dodgy things to myself to avoid periods... basically knowing I would use it to stop periods completely. On the dose of T I'm currently on I don't actually need it, but I still keep it handy and take a few every now and then just in case the body is thinking of trying to build up the uterine lining for a flush out.
My Dr. specifically told me that it doesn't interfere with T, because I asked her that, and the specialist Dr at the GIC said it as well.
On my current T dose, I get zero symptoms of female cycle. This was the dose they put me on to begin with. They thought I would have symptoms so they suggested I continue to take Norithisterone for 6 months as well. The way they instructed me to take it was daily for half a month and then to allow the cycle to complete during the latter half of the month (with reduced symptoms I guess), but I don't take it that way because I literally can't stand having the period if it's at all possible to prevent it. So I would assume they can instruct you to take progesterone pills anywhere between 1-2 times daily (depending on what your Dr. says) and in a similar way to taking birth control pills to reduce the amount of bleeding and symptoms.
I can't help you with when to take it if still having any cycle because I don't have one, But at the moment I just take one every few days just in case. I don't need it daily.