It depends on what you want, if you only take androgen blockers or SARMs (selective androgen receptor modulators) . taking androgen blockers , your body won't be producing nor using androgens (male dominant hormone) which is responsible for masculinizing , however without androgens being replaced with anything, due to lack of sexual hormones, your body will suffer, your bones will get weak, your skin and hair will get old soon , your immune system will be weak, etc, just look at eunuchs. taking SARMs will not block the production of androgens, it will just make your cells "blind" and they won't use these hormones, however they are still here and your body won't suffer from sexual hormone lack. There's different dosages for different effects, you may use these drugs only to stop baldness or your fertility. The less androgens your body use, the more feminine it gets, eventually you can develop small breasts on these drugs but that's rare.
5-alfa-reductase inhibitors can be used to demasculinize in the small degree possible.
Progesterone is also a drug without feminine effects like the above, but it can also be used to demasculinize.
Estrogens, when added to androgen blockers they have full feminizing effects, alone they still powerful, but the effects are less and your health can suffer with being on very high doses of hormones without blockers.
Bio-identitical hormones are the safest for your health tough.
And seriously, talk to your doctor first, don't self medicate.
