Weighing in at 244 pounds at 6 foot 1 I find that fat tends to redistribute a bit easier. Its all been moving from the belly area to where I want it to be. In addition having already existing man boobs they just reshaped and are a nice b/c already. In addition the cycling muscles in my legs along with fat redistribution make for a pleasingly female shaped bottom half. I've managed to get down from 264 pounds and plan on trying for 195ish. Going to take another 3-4 months to reach that goal. To me, the fact you already have a bit of excess fat helps. My biggest issue right now is the fact that I still have a lot of muscle. Not so bad for legs, but arms look a bit out of place! I've managed to fit a 16/18 womens size in most things and my old mens xl stuff fits pretty well now.
Interestingly, as compared to 3 months ago, I don't look fat. All the redistribution hides the fact that I still need to get rid of another 40 pounds or so. I'd say that starting larger makes it a bit easier. Especially since Spiro knocks the desire to eat much at all out of you, so its almost impossible not to lose weight.