The incidence rate among TS is very rare. My father died of prostate cancer in 2010, was told I was "high risk", and after putting him through the absolute mill with different ineffective "
treatment & procedures" I discovered they never gave him bicalutamide which was relatively new in 1998.
One study states:
"a (1/5th) daily dose of bicalutamide has equivalent efficacy to a corresponding flutamide . . . (and) is considered to provide equivalent survival outcome compared with castration in patients . . . (with) the benefits of a better quality of life and better palliation combination regimen. Treatment with the bicalutamide combination regimen resulted in a longer median survival than with the flutamide combination regimen"
Combining
THAT with the only positive side effects of bicalutamide (not to mention long half-life which makes healthy low dosing almost just as inexpensive as "spironolactone") I get very frustrated with the prejudice that our scripting doctors and certain members here seem to have against it. Having also had personal experience with a former member here that had an orchidectomy I know which has better outcome, is the more effective choice!!
But then again, everyone is different, results may vary??