Are you taking any other medications besides the HRT? Medication interactions could play a major role in undesired hormonal goal. For example, if you are taking any medication for seizure management such as carbamazepine (Brand: Tegretol), barbiturates (e.g. phenobarbital (Brand: Phenobarb)), or antibacterial (e.g. Rifampin (Brand: Rifadin)), they tend to lower the drug concentrations in the body. For your privacy, I wouldn't recommend you to tell us what medications you are taking but would recommend you to talk to your pharmacist if you think there might be an drug-drug interactions (Including herbal and dietary supplements!). One additional note, if you are taking spironolactone (Brand: Aldactone), it's better to take it with food because it not only reduce the side effect (upset stomach) but also increase the absorption of the drug.