I live about 60 miles north of Tampa, and I expected the worst when I started transitioning. And so far I have been completely surprised. All my neighbors are cool, my doctor's office has multiple transgender patients, and the support and social groups in St Pete and Orlando are very active. Look up Metro Health in Tampa for more support.
I'm in a completely different position that you are, considering that I'm 59 years old, semi-retired, and I was well established here, having lived in this location for 10 years before I came out, so your mileage may vary. There are bigots in every place, but so far I haven't run head-on into any.
PM me if you'd like to talk about it.
Stephanie