I also had estradiol levels well above the highest male level.
It can be a sign of certain cancers etc. The effect is also, that it makes male body sterile. Which explains, why I never had any children.
I never bothered to check if I had a cancer or not, was just happy, that the estradiol level is so high already.
And it has been about four to five years since that, so any cancer would have appeared already.
I also at the time discussed with doctor, if that would be some sort of intersex condition, but apparently not.