Quote from: Crist on July 21, 2018, 10:39:39 AM
I am writing because someone naively suggested that maybe I could try masculinizing my brain, in order to feel more comfortable with being male, taking testosterone instead of feminizing my body taking estrogen. I haven't heard anything like that and I am wondering whether it has been tried before and what the results had been. I started looking some in the internet but I haven't found the right keywords yet and thought that it might be faster to ask here.
@Crist , I have some experience with this.
At age 16 (1969-70) my parents and doctors tried to 'fix' me, through a series of weekly injections of testosterone for a few years. This was combined with some scare tactics, and counseling from our local priest.
All the testosterone did was change me from a slightly effeminate A student into an angry (and hairy!) D student. I lost the ability to concentrate on tasks, likely because of the testosterone. This improved a bit when I left home for college and later the military and stopped the injections.
It did NOT 'masculinize' the brain, a process that takes place primarily in the last trimester of fetal development and continues a bit after birth, setting up some sexually dimorphic regions primarily around the hypothalamus to function with a male body and primitive role.
In utero I was exposed starting at Week 10 to high levels of diethylstilbesterone (DES), a synthetic estrogen in Mom's prenatal vitamins that suppresses testosterone in the fetus among many other effects. I likely have the more female version of the sexually dimorphic regions.
Refer to my avatar image to see just how comfortable the treatment made me as a male...