Yes, my experience is similar to what @kendra mentioned. I had a sensation of calm, like an alarm I was barely aware of had been constantly sounding, and became silent once I started HRT. My senses became more acute, colors seemed brighter, smell and taste more acute.
One interesting item is that during the first several months of HRT, while still passing as male, the responses of other males around me changed. They tended to move in closer to me, for example, and seemed to be offering to help me more often. At one point several of us were gathered around a table working on something, and the men around me, all in their 60s and 70s, were all leaning in uncomfortably close. I suspect that there was a subtle scent cue, perhaps phemones, that had changed about me.
About 4 months into HRT I was out enjoying a very nice steak dinner with someone, and between the superbly prepared steak and sides, I experienced a very, very strong response to the taste and odor sensations. VERY strong. I felt like I should roll over and have a smoke afterwards...
For some of us, getting the right hormones corrects a long term problem with our neurochemistry from getting the wrong hormonal signals. That's where my sense of relief and improved senses came from.