I'm going through this drill for the third time. A few days past your Estradiol 'due date' you will feel more irritable, possibly have a headache, and may start experiencing hot flashes.
Welcome to womanhood, as you share an experience many women have, as their Estradiol level fluctuates. In discussions I find that my experience is shared by many perimenopausal women. As long as you recognize what you are going through, and are prepared to feel a bit cranky, you'll do OK. For folks who do not anticipate the impact, it can be uncomfortable, and bring on waves of 'down' emotions and self-doubt. Know that this is temporary, and that you will soon be back on Estradiol and feeling better.
Look out for post-op depression, which may bite a few weeks to months after surgery. In my case I strongly suspect it is tied to general anesthesia, as it has bitten after every procedure where that is used on me, whether or not transition related. I had it after Gender Confirmation Surgery (GCS) and Facial Feminization Surgery (FFS), and I have had it after cancer and bladder surgeries. Again, being aware of it, and not letting it sneak up and sink it's hooks into you helps tremendously in coping.