Hi Everyone;
I am a complete convert to Micronised Progesterone. I take Promethium (one capsule) at bedtime. I have been on Progynova for nearly 6 years now and after Promethium became available in Australia about a year ago, I persuaded my doctor to also prescribe it to me as part of my HRT. I should say that I have never been on Blockers (this time around in my "2nd" transition). Part of the reason was when I started my {2nd) transition 6 years ago my T was very low and my doctor indicated that it was the E ie Progynova that would work best.
Over the last year my Doctor initially put me on Promethium taken daily (contunously). I was on that regime for about 3 months, but I found that it really was too much for me, making me very moody and irritable (sometimes described as a bit crazy). Since I have gone onto a 2 weeks off and 2 weeks on cycle I have become so much better.
Effectively I am on an Estrogen only regime (take twice a day ) at 10am and 10pm for Days 1-14, then on Day15 I take initially 2 capsules of Promethium at 10pm as a combined regime until about Day 20-22, the slipping back to 1 capsule at night time and Proynova once a day until day 30. Around the mid month period I do get moody and a girlfriend reckons I go into a pseudo PMS stage, but after 2 days on the combined regime I am literally on top of the world. I described it elsewhere saying that for the first half of the month, I feel I just want to lounge about (jeans grungy look), but once on the combined regime after my Pseudo PMS stage, I really feel ultra feminine. I love going out with girlfriends, shopping, really focusing on looking great on my make-up (the first part of the month I probably only bother with Lipstick and eyeliner and a little mascara, spending at most 5 minutes on my make up routine. The second half I can easily spend 60 minutes getting ready to go out, wearing some great clothing combinations and feeling on top of the world, with my makeup (Bare Minerals foundation, highlighter, glow, blusher, eye shadow, eyebrows, eyeliner, mascara, lip pencil, lipstick, perfume etc etc).
After a year on the combined regime, I have had increased areola growth (almost Tanner stage 5,) my breasts have achieved larger upper pole development (I am now a Small C Cup and I have much more pronounced buttocks. (adding about 4" to them) Lots of girlfriends have commented on my new curves.
So I am a big favourite of the combined regime.
I did though get some hot flashes intially when I started on the Progesterone and also when I went onto a Cycle, which by the way mimics a Cis gender female hormone levels with Progesterone falling offer rapidly and Estrogen generally a slower curve from Days 22.
The only other thing was that when I started on it I did experience some lactation in the breasts. My doctor did pre-warn about it and has been checking my Prolactin levels. With the plan to reduce the Progesterone if I generate too much fluid. So far I haven't had the increase in fluid leakage, with Progesterone levels adequate to Cis gender female hormonal levels.
JudithLynn