Neovaginal Human Papilloma Virus–Related Squamous Cell Carcinoma in a Transgender Woman
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2816221 Malte Renz, MD, PhD, Stanford University
JAMA Network Open (March 15, 2024)
Neovaginal squamous cell carcinomas (SCCs) can occur in transgender women following gender-affirming surgery (GAS)... This unscreened reproductive tissue with high human papilloma virus (HPV) prevalence may be at increased risk of developing SCC once heterotopic and inverted, but formal recommendations regarding surgical follow-up examinations, screening, and treatment are missing...
Formalized recommendations could include routine preoperative screening of the penile-scrotal skin used for the neovagina to help risk-stratify postoperative examinations...
The fact that many transgender women retain the prostate does not preclude them from gynecologic oncology care...
Guideline recommendations for transgender women may help promote physical health and broaden health equity with the inclusion of a gender-diverse population. ------
Speaking of trans healthcare, have you and your medical care providers considered pre-surgical and post-op oncology exams and screenings?