Effect of Long-Term Administration of Cross-Sex Hormone Therapy on Serum and Uri

[Shana A]

Effect of Long-Term Administration of Cross-Sex Hormone Therapy on Serum and Urinary Uric Acid in Transsexual Persons
R. Yahyaoui, I. Esteva, J. J. Haro-Mora, M. C. Almaraz, S. Morcillo, G. Rojo-Martínez, J. Martínez, J. M. Gómez-Zumaquero, I. González, V. Hernando and F. Soriguer

http://jcem.endojournals.org/cgi/content/abstract/93/6/2230

Background: Transsexual persons afford a very suitable model to study the effect of sex steroids on uric acid metabolism.

Design: This was a prospective study to evaluate the uric acid levels and fractional excretion of uric acid (FEUA) in a cohort of 69 healthy transsexual persons, 22 male-to-female transsexuals (MFTs) and 47 female-to-male transsexuals (FMTs). The subjects were studied at baseline and 1 and 2 yr after starting cross-sex hormone treatment.

Results: