Does micronized progesterone interfere with Estrogen receptors?

[melanie2009]

Ive read som much about the pros and cons of adding a progesterone.
Does micronized progesterone interfere with Estrogen receptors? Does it raise T-levels? 

Id appreciate to hear others peoples advice and experience on this.

Melanie

[rejennyrated]

Ive read som much about the pros and cons of adding a progesterone.
Does micronized progesterone interfere with Estrogen receptors? Does it raise T-levels? 

Id appreciate to hear others peoples advice and experience on this.

Melanie

All forms of progesterone will moderate the interaction of estrogen - that is why combined HRT is often referred to as "opposed hormone therapy" in medical journals. So you end up taking a slightly higher dose of E.

The point is though that progesterone does other things as well - for exmaple it changes your mood, it has an affect on your osmotic balance and hence blood pressure... etc etc.

My experience after 25 years taking a combined HRT regimen is that the balance of benefits outweighs the cons.

As far as T level are concerned - I don't know - the only thing I do know is that mine are pretty well bang on right for a natal female, (just fractionally low but within the margin of error) which is surely what one should aim for as a very low T level leads to lack of sex drive and all sorts of other problems.

[melanie2009]

Thanks for the reply. Can you explain to me what you mean by

So you end up taking a slightly higher dose of E

. You mean that whilst on progesterone, the levels of Estrogen have to be increased to compensate.?

Melanie

[rejennyrated]

yes - some people take a very slightly higher dose of estrogen - but really only a very small increase.

And like I say you do need to get an endocrinologist or other medically trained person to design and supervise the program until you know for sure how it is working for your body.

[Autumn]

Last time I had my bloodwork done, I was at the height of my P cycle and my T count was still as low as he wanted it. I personally have not been taking extra E while cycling. My breasts seem to be coming along quite well. But of course HRT is a horribly inexact science and everybody's body reacts differently.