Hi Michelle,
I don't know whether Spiro makes your urine discoloured as I don't have any experience with it (yet, although this is set to change soon) but there are several reasons why your pee would be a funny colour and it is only (sometimes) very loosely linked to drug use, the most common reason is that you are dehydrated and the toxins become concentrated, it can also be a sign that of stress to your Liver or Kidneys. Trust me, from the harrowing memories of conducting way too many drug screens, pee comes in all kinds of colours (and smells, urrggh!!) so yours probably won't set off any flags, if the colour concerns you, try drinking more water, and if that doesn't help, ask your doc if it might be the Spiro.
Take care Milllie.